Microneedling with Exosomes

Refresh Your Skin

Skincare has gone micro. Microneedling with exosomes is a cosmetic treatment that rejuvenates the skin and reduces the signs of aging. This procedure is similar to a “vampire facial” or microneedling with PRP injections, but exosomes are much more powerful. They can help treat a wide range of skin problems by rebuilding collagen, tightening and sculpting facial muscles, clearing pores, and minimizing uneven texture (including the appearance of scarring). The effectiveness of microneedling with exosomes has been making waves in social media, with even some beauty bloggers and influencers sharing their positive experiences and results!

  1. CONCERN: Uneven texture, acne scarring, and clear skin.
  2. TREATMENT TIME: 45-60 minutes.
  3. RESULTS: Improved appearance to the skin.

What is Microneedling with Exosomes and How Does it Work?

We may not be able to prevent getting older, but we can take active steps to reverse signs of aging on our skin. Microneedling with exosomes is a powerful combination therapy that can help to address a wide range of skin concerns. Collagen induction therapy (CIT), better known as microneedling, is one of the best non-surgical treatments available when it comes to improving the texture and appearance of fine lines, wrinkles, and other visible signs of aging.

Microneedling is a versatile and minimally invasive procedure that has gained widespread recognition for its transformative effects on the skin. This treatment works by using fine, sterile needles to create controlled micro-injuries on the skin’s surface. These tiny micro-injuries stimulate the skin’s natural healing process, stimulating collagen production and cellular turnover.

Exosomes are a class of cell-derived extracellular vesicles of endosomal origin. They contain growth factors, cytokines, and other bioactive molecules that play a pivotal role in cell communication and tissue repair. Many doctors believe that exosomes may be more important than stem cells due to their unique ability to function as “messengers” within the body, transferring information from cell to cell. When applied to the skin, exosomes stimulate cell regeneration, enhance collagen production, and promote the overall rejuvenation of damaged or aging skin.

What Are the Benefits of Microneedling with Exosomes?

Microneedling is safe and one of the most effective ways to improve the texture of your skin.. Although the needles make tiny puncture marks in your skin’s surface, they do not cause any harm or injury. These channels not only encourage collagen and elastin production but also enhance the absorption of topically applied skincare products, maximizing their efficacy. Microneedling with exosomes will get you significantly greater results with each single treatment.

But the best benefit of exosome therapy is that it is a natural and safe treatment option. Exosomes are derived from the patient’s cells or a donor with a closely matched genetic profile, thus, there is little risk of an adverse reaction or rejection.

The benefits of microneedling with include:

  • Improved skin texture
  • Enhanced skin elasticity
  • Smaller pores
  • Enhanced collagen production
  • Reduced inflammation
  • Minimal downtime

Your body continues to produce extra collagen for a few months after the treatment, so you should notice that the appearance of your skin improves for months after your final appointment. At SKIN FIVE, we understand that every client is unique, and their skincare needs vary. Our commitment to providing personalized care is what sets us apart. Call us today to schedule a consultation.

What You Can Expect From Your Session

The process takes 60 minutes on average, with most patients requiring 4-6 sessions to notice an improvement.

The microneedling process starts with a thorough consultation with your SKIN FIVE provider to determine your skincare needs and aesthetic goals. During treatment, a specialized microneedling device is used to create precise, microscopic channels in the skin. These channels not only stimulate collagen and elastin production but also enhance the absorption of topical skincare products, making them more effective when combined with exosomes.


How long does this treatment take?

Your treatment session lasts approximately 30 minutes depending on areas treated. Can be combined with other face services.

What areas can I treat?

Our SKIN FIVE providers can perform microneedling on various body areas, including the face, neck, décolletage, and even the hands.

When can I see results?

Expect optimal results after about 4-6 weeks.

Where are these treatments performed?

At SKIN FIVE, we provide best in class treatment rooms equipped with complimentary wi-fi so you can plug into your favorite playlist or continue your Netflix binge.

What do I need to wear?

We recommend you dress for comfort. Many of our patients come wearing workout clothing. If you’re on any special oral or topical medications, please let us know when you schedule your appointment and we will let you know how to prep.

Who is this treatment designed for?

Because this treatment works for different types of skin and skin issues, almost everyone can benefit from Before any treatment, our SKIN FIVE providers perform an assessment to learn about your concerns and design a treatment plan to deliver results.

Are there any special discounts I can apply?

SKIN FIVE offers a unique discount program called HIGH FIVE membership. Members receive a 15% discount on all packages and products, as well as select services, while their membership is active.

Does it hurt?

Most people don’t experience any discomfort after microneedling. However, patients may experience some sensitivity or tenderness in the treated areas. In most cases, this only lasts for 24-48 hours.


"It's the perfect marriage of science and beauty, offering a rejuvenating and transformative experience that enhances skin's natural radiance. By combining the power of micro-needling with the regenerative potential of exosomes, we're able to unlock your skin's true potential, helping you look and feel your best."

Elisabeth Dzhandzhikyan, RN

SKIN FIVE Pacific Palisades